| 消痰散结方对裸鼠MKN-45人胃癌组织中VEGF-C及其受体VEGFR-3表达的影响 |
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| 引用本文： | 庞斌,魏品康,李勇进,毛竹君. 消痰散结方对裸鼠MKN-45人胃癌组织中VEGF-C及其受体VEGFR-3表达的影响[J]. 中国中西医结合杂志, 2011, 31(2): 204-208 |
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| 作者姓名： | 庞斌 魏品康 李勇进 毛竹君 |
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| 作者单位： | 第二军医大学附属长征医院中医科,上海,200003 |
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| 摘 要： | 目的 观察消痰散结方对裸鼠MKN-45人胃癌组织中血管内皮生长因子C(vascular endothelial growth factor-C，VEGF-C)及血管内皮生长因子受体3(vascular endothelial growth factor receptor-3，VEGFR-3)表达的影响，探讨消痰散结方防治胃癌淋巴转移的作用机制。
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| 关 键 词： | 消痰散结方；胃肿瘤；血管内皮生长因子；血管内皮生长因子受体；转移 |
Effect of Xiaotan Sanjie Recipe on Expressions of VEGF-C and VEGFR-3 in Nude Mice with Transplanted Human Gastric Adenocarcinoma Cell MKN-45 |
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| PANG Bin,WEI Pin-kang,LI Yong-jin,et al. Effect of Xiaotan Sanjie Recipe on Expressions of VEGF-C and VEGFR-3 in Nude Mice with Transplanted Human Gastric Adenocarcinoma Cell MKN-45[J]. Chinese journal of integrated traditional and Western medicine, 2011, 31(2): 204-208 |
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| Authors: | PANG Bin WEI Pin-kang LI Yong-jin et al |
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| Affiliation: | PANG Bin,WEI Pin-kang,LI Yong-jin,et al Department of Traditional Chinese Medicine,Changzheng Hospital,Second Military Medical University,Shanghai (200003) |
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| Abstract: | Objective To observe the mechanism of Xiaotan Sanjie Recipe (XSR) in inhibiting lymphatic metastasis of gastric carcinoma by observing its effects on the expressions of vascular endothelial growth factor-C (VEGF-C) and its receptor VEGFR-3 in nude mice with transplanted human gastric adenocarcinoma cell MKN-45. Methods Thirty mice were made into MKN-45 tumor model and randomly divided into three groups treated with saline,5-Fu,and XSR,respectively. Gene and protein expressions of VEGF-C and VEGFR-3 in the t... |
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| Keywords: | Xiaotan Sanjie Recipe gastric carcinoma vascular endothelial growth factor vascular endothelial growth factor receptor metastasis |
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