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| 肝癥口服液含药血清对肝癌细胞SMMC-7721细胞增殖的影响 | |
| 引用本文： | 宋海澄,王燕云,姚树坤,陆艳萍,韩依轩,舒荣,崔刘福. 肝癥口服液含药血清对肝癌细胞SMMC-7721细胞增殖的影响[J]. 中国中医基础医学杂志, 2006, 12(3): 190-191,197 |
| 作者姓名： | 宋海澄 王燕云 姚树坤 陆艳萍 韩依轩 舒荣 崔刘福 |
| 作者单位： | 1. 华北煤炭医学院,附属开滦医院,河北,唐山,063000 2. 唐山市妇幼保健院,河北,唐山,063000 3. 河北医科大学,第四临床医院,河北,石家庄,050011 |
| 摘 要： | 目的:探讨肝口服液含药血清对肝癌细胞SMMC-7721细胞增殖的影响,为临床应用肝口服液治疗肝癌提供实验室依据。方法:选取Ⅱb或Ⅲ期肝癌病人和健康志愿者各5例,分别在用药前及用药后8周采集血清,与SMMC-7721细胞共同培养24h、48h后,应用噻唑氮蓝(MTT)比色法测定肝癌细胞SMMC-7721增殖水平。结果:HCC患者含药血清对SMMC-7721细胞增殖抑制率在24h、48h分别为45.00%3、9.32%;而健康志愿者为4.58%、7.70%,HCC患者含药血清对肝癌细胞增殖抑制作用明显高于健康志愿者。结论:肝口服液含药血清对SMMC-7721细胞的增殖有明显的抑制作用并促进其凋亡,表明肝口服液有抗肿瘤作用。 |
| 关 键 词： | 肝癥口服液 肝癌细胞 增殖 含药血清 |
| 文章编号： | 1006-3250（2006）03-0190-02 |
| 收稿时间： | 2005-07-09 |
| 修稿时间： | 2005-07-09 |
Efficacy of the GANZHENG Solution Containing Serum in Inhibiting the Proliferation of Hepatocarcinoma SMMC-7721 Cell Line |
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| SONG Hai-cheng,WANG Yan-yun,YAO Shu-kun,LU Yan-ping,HAN Yi-xuan,SHU Rong,CUI Liu-fu. Efficacy of the GANZHENG Solution Containing Serum in Inhibiting the Proliferation of Hepatocarcinoma SMMC-7721 Cell Line[J]. Chinese Journal of Basic Medicine In Traditional Chinese Medicine, 2006, 12(3): 190-191,197 | |
| Authors: | SONG Hai-cheng WANG Yan-yun YAO Shu-kun LU Yan-ping HAN Yi-xuan SHU Rong CUI Liu-fu |
| Affiliation: | 1. The Affiliated Kailuan Hospital of Northern China Coal Medical College, Tangshan, Hebei 063000, China ; 2. The Maternal and Child Health Hospital of Tangshan , Tangshan , Hebei 063000, China ; 3. The Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, China |
| Abstract: | |
| Keywords: | SMMC-7721 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |