| 灰黄霉素中灰黄霉酸杂质及色泽的考查 |
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| 引用本文： | 常仁厚.灰黄霉素中灰黄霉酸杂质及色泽的考查[J].中国现代应用药学,1998,15(5):44-45. |
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| 作者姓名： | 常仁厚 |
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| 作者单位： | 江苏丰县药品检验所,丰县,221700 |
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| 摘 要： | 目的：本文采用薄层色谱法考查了不同厂家灰黄霉素中灰黄霉酸杂质的存在。方法；以丙酮为溶媒，精制灰黄霉素，摸索分离条件，探讨杂质限度，考查产品色泽。结果：杂质均值为０．２７６％，ＲＳＤ为０．１６８％。结论：对改进产品检验方法，提高产品质量具有一定的参考价值。
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| 关 键 词： | 灰黄霉素 灰黄霉酸 薄层 分离 杂质 色泽 |
Examination of griseofulvin acid in of griseofulvin by thin layer chromatography |
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| Chang Renhou.Examination of griseofulvin acid in of griseofulvin by thin layer chromatography[J].The Chinese Journal of Modern Applied Pharmacy,1998,15(5):44-45. |
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| Authors: | Chang Renhou |
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| Abstract: | OBJECTIVE: To examine griseofulvin acid in griseofulvin by TLC. METHODS: Using acetone as solution, purified griseofulvin, found out the conditions to separate griseofulvin acid from griseofulvin, search out the limit of its contents, inspect and compare the lustre of griseofulvin. RESULTS: The average content of griseofulvin acid is 0.276 % , the RSD is 0.168% .CONCLUSION:The method is great useful to improve the procedure of drug control,and more useful to improve the quality of griseofulvin. |
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| Keywords: | griseofulvin griseofulvin acid examination thin layer chromatography |
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