| HPLC法测定吗氯贝胺片含量 |
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| 引用本文： | 王守箐,徐斌. HPLC法测定吗氯贝胺片含量[J]. 齐鲁药事, 2004, 23(2): 20-21 |
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| 作者姓名： | 王守箐 徐斌 |
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| 作者单位： | 鲁南制药股份有限公司,临沂,276003 |
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| 摘 要： | 目的 建立了一种测定吗氯贝胺的HPLC新方法。方法 在室温下以甲醇∶水(30∶70 )为流动相,检测波长为2 4 0nm,流速为 1 0ml·min-1。结果 吗氯贝胺在 2 5～ 80 μg·ml-1范围内呈良好线性,最低检测限为 3 0ng,回收率为 98 9～10 0 2 %。结论 本法简便,准确,重现性好,可用于本制剂的含量测定及质量控制
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| 关 键 词： | 吗氯贝胺 HPLC |
| 文章编号： | 1672-7738(2004)02-0020-02 |
Determination of Moclobemide by HPLC |
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| Wang shou-qing,Xu BinLu'nan Pharmaceutical Share Limited Corporation,Linyi,). Determination of Moclobemide by HPLC[J]. qilu pharmaceutical affairs, 2004, 23(2): 20-21 |
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| Authors: | Wang shou-qing Xu BinLu'nan Pharmaceutical Share Limited Corporation Linyi ) |
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| Affiliation: | Wang shou-qing,Xu BinLu'nan Pharmaceutical Share Limited Corporation,Linyi,276003) |
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| Abstract: | Objective To establish a HPLC method for the determination of Moclobemide. Methods Ethanol and water (30∶70) as mobile phase , detected at a wavelength of 240nm, flow rate was 1.0ml·min -1. Results Good linearity was showed in the concentration of 2.5～80μg·ml -1, detect limit was 3.0ng, the recovery was 98.9～100.2%. Conlusion The method was simple, accurate and repeatable. This method can be used as a quantity control method of determination of Moclobemide. |
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| Keywords: | Moclobemide HPLC |
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