| 测定糖尿病肾病患者血浆D-二聚体含量的临床意义 |
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| 引用本文： | 邢广群,孙建平,杨洁. 测定糖尿病肾病患者血浆D-二聚体含量的临床意义[J]. 青岛医药卫生, 1999, 0(6) |
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| 作者姓名： | 邢广群 孙建平 杨洁 |
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| 作者单位： | 青岛大学医学院附属医院 266003(邢广群，孙建平)，青岛大学医学院附属医院 266003(杨洁) |
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| 摘 要： | 目的 探讨糖尿病肾病患者凝血和纤溶方面的特点。方法 选取血浆D-二聚体作为研究指标,分别测定糖尿病肾病、尿毒症组和慢性肾小球肾炎、尿毒症组血浆D-二聚体含量进行对照研究,D-二聚体用单抗 ELISA双抗体夹心法进行定量测定。结果 糖尿病肾病组血浆D-二聚体含量显著高于慢性肾小球肾炎组,且二者D-二聚体含量皆高于正常值。结论 糖尿病肾病患者存在明显的高凝与继发性纤溶亢进。
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| 关 键 词： | 糖尿病肾病 慢性肾小球肾炎 D-二聚体 |
The Clinical Signficance of Determing Plasma D-dimer Level in patients with Diabetic Nephropathy |
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| Xing Guangqun,et al.. The Clinical Signficance of Determing Plasma D-dimer Level in patients with Diabetic Nephropathy[J]. QINGDAO Medical Journal, 1999, 0(6) |
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| Authors: | Xing Guangqun et al. |
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| Affiliation: | Xing Guangqun,et al. Affiliated Hospital of Qingdao Medical College,Qingdao 266003 |
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| Abstract: | Objective To investigate the character of blood - clotting and fibrinolysis in diabetic nephropathy patients. Methods Determine plasma D-dimer in two groups of uremic patients diabetic nephropathy and chronic nephritis. D-dimer was determined quantitatively by enzyme linked immunosorbent assay. ELISA of double antibody-sandwiched method. Results D-dimer of the diabetic nephropathy group was significantly higher than the chronic nephritis group. D-dimer of both groups was higher than the normal range. Conclusion There is significantly hypercoagulation and secondary hyperfibrinolysis in diabetic nephropathy patients. |
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| Keywords: | Diabetic nephropathy Chronic nephritis D-dimer |
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