膝关节注射玻璃酸钠治疗骨关节炎112例临床效果

目的观察膝关节内注射玻璃酸钠对膝关节骨关节炎的疗效。方法总结1998年9月至2010年8月门诊和住院按疗程关节内注射玻璃酸钠的膝关节骨关节炎患者112例,玻璃酸钠20mg关节腔内注射,1周1次。连续注射5周后评定疗效。术前Lyshlom膝关节功能评分（64.8±3.0）。通过6个月～5年的随访,观察患者自我评价、下蹲活动及运动疼痛、关节肿胀、跛行、支撑、膝关节屈伸活动度等临床表现。结果治疗后膝关节功能明显改善,Lyshlom膝关节功能评分（90.0±1.4）。优良率91.96%。结论玻璃酸钠关节内注射可明显减轻膝关节的局部症状,增加关节的活动度,恢复膝关节的功能。

The Clinical Effect of Injection of Sodium Hyaluronate in Treating Knee Osteoarthritis of 112 Cases

Objective To observe the efficacy of the knee joint injection of sodium hyaluronate on knee osteoarthritis. Methods 112 outpatients and inpatients with knee osteoarthritis who were given the intra-articular injection of sodium hyaluronate from September 1998 to August 2010 were summarized,20 mg sodium hyaluronate was injected in intra-articular,one time for one week. The curative effect was evaluated after continuous injection for 5 weeks. Lyshlom knee joint function score before surgery was（64.8 ± 3.0） . Through the follow-up of 6 months to 5 years,the patients＇ self-evaluation,squatting activities and movement pain,joint swelling,limps,support,knee range of motion and other clinical manifestations were observed. Results After the treatment,knee joint function improved significantly,Lyshlom knee joint function score was（90.0 ± 1.4） . The excellent and good rate was 91.96%. Conclusion Intra-articular injection of sodium hyaluronate can significantly reduce the local symptoms of knee joint,and increase joint activity and restore knee joint function.