Serum monoclonal component and nephrotic syndrome--it is not always amyloidosis. Diagnosis: WM complicated by retroperitoneal and renal infiltration and associated with a minimal change disease.
Department of Nephrology, H?pital Necker-Enfants Malades, 149-161 rue de Sèvres, 75743 Paris cedex 15, France.
Abstract:
Case
In March 2005, a 55-year-old woman was referred to our hospitalfor sudden onset of diffuse oedema. Her past medical historywas remarkable for an IgM-monoclonal gammapathy of unknown significance,diagnosed in December 2004. On admission, she complained of abdominal pain; physical examinationshowed diffuse oedema with a weight gain of 4 kg. Blood testsrevealed normocytic anaemia (haemoglobin 9.5 g/dl) with normalwhite blood cell (5.2 x 109/l)