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Derivate isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis |
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| Authors: | Chen Lijuan Tian Hua Li Meng Ge Chao Zhao Fangyu Zhang Lixing Li Hong Liu Junxi Wang Tingpu Yao Ming Li Jinjun |
| Affiliation: | 1.Shanghai Medical College, Fudan University, Shanghai, China ;2.State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Jiaotong University School of Medicine, Shanghai, China ;3.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory Fornatural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China ;4.College of Life Sciences and Chemistry, Tianshui Normal University, Tianshui, China ; |
| Abstract: | Tumor Biology - We have previously demonstrated that isocorydine (ICD) can be served as a potential antitumor agent in hepatocellular carcinoma (HCC). A novel derivate of isocorydine (d-ICD) could... |
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