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生育及激素依赖性癌症的疫苗与被动免疫研究
引用本文:Talw.,GP 吕年青. 生育及激素依赖性癌症的疫苗与被动免疫研究[J]. 中华男科学杂志, 2000, 6(2): 77-88
作者姓名:Talw.  GP 吕年青
作者单位:InternationalCentreforGeneticEngineeringandBiotechnology!ArunaasafAliMarg,NewDelhi,India,TalwarResearchFoundation,E6,NebValley,NebSarai,NewDelhi,India
基金项目:CurrentworkofG .P .TalwarissupportedbyresearchgrantsfromtheRockefellerFoundationandtheTalwarResearchFoundation .
摘    要:总结了人绒毛膜促性腺激素 (hCG)避孕疫苗的开发研究。这类疫苗能阻止性活跃妇女受孕而不损害排卵 ,也不扰乱月经规律。同时还总结了有关诱导针对黄体释放激素抗体的疫苗研究 ,以及这类疫苗在包括前列腺肥大和其它性激素相关的男女癌症的免疫治疗方面的应用。主张应用人源性重组抗激素抗体的被动免疫方法来保证有效、安全、迅速的治疗

关 键 词:生育调节  人绒毛膜促性腺激素  疫苗  黄体释放激素  前列腺肥大  被动免疫  治疗
修稿时间:2000-04-23

Vaccines and Passive Immunological Approaches for the Control of Fertility and Hormone dependent Cancers
G.Talwar. Vaccines and Passive Immunological Approaches for the Control of Fertility and Hormone dependent Cancers[J]. National Journal of Andrology, 2000, 6(2): 77-88
Authors:G.Talwar
Abstract:WT5”BZ]This article summarizes the development of a vaccine against the human chorionic gonadotropin that prevents pregnancy in sexually active women without impairment of ovulation or derangement of menstrual regularity. Also summarized are the vaccines inducing antibodies aginst the luteinizing hormone releasing hormone, which have immunotherapeutic potential in prostatic hypertrophy and other sex hormone dependent male and female cancers. The adoption of passive immunization using humanized recombinant anti hormone antibodies is advocated for assured efficacy and safe, prompt therapeutic action. (With the Chinese translation by Nian Qing LU) [WT5”HZ]
Keywords:WT5”BZ]Fertility regulation   Human chorionic gonadotropin (hCG)   Vaccine   Luteinizing hormone releasing hormone   Prostatic hypertrophy   Passive immunization   Therapy
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