Metabolic syndrome and gender differences in postprandial lipaemia. |
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| Authors: | Genovefa D Kolovou Katherine K Anagnostopoulou Antonis N Pavlidis Klelia D Salpea Stella A Iraklianou Ioannis S Hoursalas Dimitri P Mikhailidis Dennis V Cokkinos |
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| Institution: | First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. genkolovou@nail.gr |
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| Abstract: | BACKGROUND: Postprandial hyperlipidaemia may be a predictor of vascular risk. DESIGN: We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS). METHODS: Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load. RESULTS: Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC. CONCLUSIONS: Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance. |
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