不同类型音乐对缓解乳腺癌患者化疗焦虑、抑郁的效果研究

目的:探讨不同类型音乐对缓解乳腺癌术后患者化疗焦虑、抑郁的作用。方法:将首次接受化学治疗的乳腺癌改良根治术后120例患者分为莫扎特音乐干预组(莫扎特音乐+化疗)40例、梁祝音乐干预组(梁祝音乐+化疗)40例和对照组(单纯化疗)40例,检测3组肿瘤患者的抑郁及焦虑自评量表(SDS、SAS)、汉密尔顿抑郁及焦虑量表(HAMD、HAMA)和生活质量评定(QLQ-CCC)指标的变化。结果:对照组化疗后SDS、SAS、HAMD和HAMA与化疗前比较差异无统计学意义(P>0.05),化疗后QLQ-CCC明显低于化疗前差异有统计学意义(P<0.01);莫扎特音乐干预组化疗后SDS、SAS、HAMD和HAMA低于化疗前但差异无统计学意义(P>0.05),化疗后QLQ-CCC与化疗前差异无统计学意义(P>0.05);梁祝音乐干预组化疗后SDS、SAS、HAMD和HAMA明显低于化疗前差异有统计学意义(P<0.01),化疗后QLQ-CCC与化疗前差异无统计学意义(P>0.05)。结论:梁祝音乐能明显降低乳腺癌化疗患者的焦虑、抑郁及提高患者生活质量;莫扎特音乐降低乳腺癌化疗患者的焦虑、抑郁不明显,但不会降低患者生活质量。

Effect of different types of music to alleviate the chemotherapy anxiety and depression of the patients with breast cancer

Objective:To explore the effect of different types of music to ease the breast cancer patients after chemotherapy anxiety and depression.Methods:A total of 120 patients who would be received the first chemotherapy after modified radical mastectomy were randomly divided into 3 groups: Mozart intervention group(Mozart+ chemotherapy)(40 cases),lovers music intervention group(Butterfly music+ chemotherapy)(40 cases) and control group(chemotherapy alone)(40 cases).The self-rating scale of depression and anxiety(SDS,SAS),the scale of Hamilton depression and anxiety(HAMD,HAMA) and the assessment of life quality(QLQ-CCC) were observed in the three groups.Results:In control group,the differences of SDS,SAS,HAMD and HAMA between before and after chemotherapy were not statistically significant(P>0.01),but QLQ-CCC after chemotherapy was significantly lower than those before chemotherapy(P<0.01).In Mozart music intervention group,SDS,SAS,HAMD and HAMA after chemotherapy were lower than those before chemotherapy,but the differences were not significant(P>0.01),the QLQ-CCC was also without significant difference between before and after chemotherapy(P>0.01).In butterfly music intervention group,SDS,SAS,HAMD and HAMA after chemotherapy were significantly lower than before chemotherapy,the differences were significant(P<0.01),QLQ-CCC was no significant difference between before and after chemotherapy(P>0.01).Conclusion:Butterfly music can significantly reduce anxiety,depression of breast cancer patients after chemotherapy,and improve life quality of the patients;Mozart music can reduce anxiety,depression of breast cancer patients after chemotherapy,but not reduce the life quality of the patients.