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CT引导下经皮穿刺兔肺癌模型并发症的研究
引用本文:王运仓,赵君禄,王欣,朱振龙,刘强,刘金锋,王争,田勍,李建科.CT引导下经皮穿刺兔肺癌模型并发症的研究[J].中国医药导报,2013,10(3):24-25,28.
作者姓名:王运仓  赵君禄  王欣  朱振龙  刘强  刘金锋  王争  田勍  李建科
作者单位:河北医科大学第一医院胸外科;河北医科大学第一医院放射科;河北医科大学第一医院病理科
基金项目:河北省医学科学研究重点课题(课题编号:20100052)
摘    要:目的探讨CT引导下对兔肺癌模型活检针经皮肺组织检查时并发症的发生概率。方法成功建立41只兔肺癌模型,至肺部肿瘤长至直径1 cm,每只家兔在CT引导下实施经皮肺活检针检活检5次,总共205次,统计及分析并发症的概率。结果 41只兔肺癌模型中,19只发生并发症(46.3%),其中7只发生单纯气胸,5只发生单纯胸腔出血,7只出现胸腔出血合并气胸的情况。总计14只发生气胸(34.2%),共有12只发生胸腔出血(29.3%)。结论活检针经皮肺组织检查在兔肺癌模型可行,但出血、气胸并发率高。提示应用在人肺癌患者多次穿针时应根据患者情况谨慎选择,尽量避免并发症的发生。

关 键 词:肺肿瘤  穿刺活检  并发症  计算机X线体层摄影术

Study of complications of CT-guided percutaneous lung biopsy in rabbit model
WANG Yuncang,ZHAO Junlu,WANG Xin,ZHU Zhenlong,LIU Qiang,LIU Jinfeng,WANG Zheng,TIAN Qing,LI Jianke.Study of complications of CT-guided percutaneous lung biopsy in rabbit model[J].China Medical Herald,2013,10(3):24-25,28.
Authors:WANG Yuncang  ZHAO Junlu  WANG Xin  ZHU Zhenlong  LIU Qiang  LIU Jinfeng  WANG Zheng  TIAN Qing  LI Jianke
Institution:1.Department of Thoracic Surgery,the First Hospital of Hebei Medical University,Hebei Province,Shijiazhuang 050031,China;2.Department of Radiology,the First Hospital of Hebei Medical University,Hebei Province,Shijiazhuang 050031,China;3.Department of Pathology,the First Hospital of Hebei Medical University,Hebei Province,Shijiazhuang 050031,China
Abstract:Objective To explore the occurrence probability of complications caused by CT-guided percutaneous pulmonary puncture biopsy in rabbit model.Methods Forty-one rabbit lung cancer models were successfully established.Each rabbit was percutaneous pulmonary puncture biopsy by 5 times after the lung tumor grew to diameter of 1 cm,total of 205 times.The probability of complications were counted and analyzed.Results After biopsy in 41 rabbits,complications occurred in 19 cases(46.3%),including 7 case of simple pneumothorax,5 cases of simple pulmonary hemorrhage and 7 cases of complication of pulmonary hemorrhage and pneumothorax.Totally,14 cases were pneumothorax(34.2%),and 12 cases were pulmonary hemorrhage(29.3%).Conclusion CT-guided percutaneous pulmonary puncture biopsy in rabbit model is viable.The results suggest that CT-guided percutaneous pulmonary puncture biopsy is cautious in human lung cancer patients to avoid the occurrence of complications.
Keywords:Pulmonary neoplasm  Puncture biopsy  Complication  CT
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