| 抗病毒联合血浆置换治疗慢性重型乙型肝炎的疗效 |
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| 引用本文： | 谭可平,李孟英,覃国琦. 抗病毒联合血浆置换治疗慢性重型乙型肝炎的疗效[J]. 西南国防医药, 2011, 21(12): 1313-1316. DOI: 10.3969/j.issn.1004-0188.2011.12.013 |
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| 作者姓名： | 谭可平 李孟英 覃国琦 |
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| 作者单位： | 解放军303医院肝病中心,南宁,530021 |
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| 摘 要： | 目的总结抗病毒联合血浆置换治疗慢性重型乙型肝炎的疗效。方法收集给予人工肝血浆置换治疗的慢性乙型重型肝炎患者156例临床资料,分为抗病毒组63例（拉米夫定或恩替卡韦）和非抗病毒组93例,分析两组治疗效果、HBV-DNA阳性率及肝功能检查结果。结果抗病毒组总有效率（54.0%）显著高于非抗病毒组（38.7%）;病死率（33.3%）显著小于非抗病毒组（52.7%）;HBV-DNA阳性率（26.5%）小于非抗病毒组（50.0%）;TB、ALT、AST、PT均显著低于非抗病毒组;拉米夫定与恩替卡韦组有效率、病死率、HBV-DNA阳性率无显著差异。结论抗病毒联合血浆置换可显著提高慢性重型乙型肝炎患者的生存率。
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| 关 键 词： | 慢性乙型重型肝炎 拉米夫定 恩替卡韦 血浆置换 |
Curative effects of antiviral therapy combined with plasmapheresis on patients with chronic severe type B hepatitis |
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| Tan Keping,Li Mengying,Qin Guoqi. Curative effects of antiviral therapy combined with plasmapheresis on patients with chronic severe type B hepatitis[J]. Medical Journal of National Defending forces in Southwest China, 2011, 21(12): 1313-1316. DOI: 10.3969/j.issn.1004-0188.2011.12.013 |
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| Authors: | Tan Keping Li Mengying Qin Guoqi |
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| Affiliation: | Tan Keping,Li Mengying,Qin Guoqi Center of Liver Disease,Hospital 303 of PLA,Nanning,Guangxi,530021,China |
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| Abstract: | Objective To analyze the curative effects of antiviral therapy combined with plasmapheresis on patients with chronic severe type B hepatitis.Methods The clinical data of 156 patients with chronic severe type B hepatitis receiving the artificial hepatic plasmapheresis were collected.They were divided into antiviral treatment group who received lamivudine or entecavir(63 cases)and non-antiviral treatment group(93 cases).The curative effects,HBV-DNA positive rate and results of liver function test were compare... |
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| Keywords: | chronic severe type B hepatitis lamivudine entecavir plasmapheresis |
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