| 钝顶螺旋藻多糖对急性白血病病人NK细胞的作用 |
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| 引用本文： | 曾波航,王光明,曾亚仑. 钝顶螺旋藻多糖对急性白血病病人NK细胞的作用[J]. 中国海洋药物, 2000, 19(6): 45-47 |
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| 作者姓名： | 曾波航 王光明 曾亚仑 |
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| 作者单位： | 1. 广州医学院第二附属医院,广州,510260
2. 广州市白云山中药厂 |
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| 摘 要： | 目的：探讨螺旋藻多糖（ＳＤＰ）对白血病患者免疫功能的作用，观察了ＳＰＰ对正常人及急性白血病患者外周血ＮＫ细胞的影响。结果 ＳＰＰ可提高不同病期白血病患者ＮＫ细胞活性，但不影响正常人ＮＫ细胞活性，毒性试验表明ＳＰＰ对白血病细胞无毒性作用。结论 ＳＰＰ作为生物反应调节剂用于白血病治疗可提高ＮＫ细胞活性，值得进一步研究、开发、应用。
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| 关 键 词： | 急性白血病 NK细胞 钝顶螺旋藻多糖 治疗 |
STUDY ON EFFECT OF SPIRULINA PLATEN SIS POLYSACCH-ARIDE ON NK CELLS FROM ACUTE LEUKEMIA PATIENT IN VITRO |
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| Zeng Bohang,Wang Guangming,Zeng Yalun. STUDY ON EFFECT OF SPIRULINA PLATEN SIS POLYSACCH-ARIDE ON NK CELLS FROM ACUTE LEUKEMIA PATIENT IN VITRO[J]. Chinese Journal of Marine Drugs, 2000, 19(6): 45-47 |
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| Authors: | Zeng Bohang Wang Guangming Zeng Yalun |
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| Abstract: | AIM:The Effects of Spirulina Platensis Polysaccharide (SPP)on peripheral NK cell from healthy persons and acute leukemia patients were studied.METHODS:The activities of NK cell on target cell K 562 was measured with MTT method.RESULTS:The results showed that SPP could argument the NK cell activity from varies peroid cases with acute leukemia.SPP had no activity on NK cell from normal person.Cytotoxicity did not present when the peripheral blood mononuclear cell were co incubated with SPP.CONCLUSION:These results suggested that SPP could be exploited and utilized as an approach of biological responsive modifier therapy in the treatment of acute leukemia. |
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| Keywords: | Acute leukemia NK cell Spirulina Platensis Polysaccharide |
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