| 甘油氯化钠注射液细菌内毒素检查法的研究 |
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| 引用本文： | 张浩,张大萍,林玉洪,王震. 甘油氯化钠注射液细菌内毒素检查法的研究[J]. 淮海医药, 2005, 23(6): 438-439 |
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| 作者姓名： | 张浩 张大萍 林玉洪 王震 |
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| 作者单位： | 蚌埠医学院第一附属医院,药剂科,安徽,蚌埠,233004;蚌埠医学院第一附属医院,药剂科,安徽,蚌埠,233004;蚌埠医学院第一附属医院,药剂科,安徽,蚌埠,233004;蚌埠医学院第一附属医院,药剂科,安徽,蚌埠,233004 |
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| 摘 要： | 目的介绍细菌内毒素法对甘油氯化钠注射液热原的研究。方法应用鲎试剂检查甘油氯化钠注射液的热原,观察甘油氯化钠注射液对细菌内毒素检查法的干扰现象。结果甘油氯化钠注射液稀释2倍对细菌内毒素检查法无干扰行为。结论对甘油氯化钠注射液进行2倍稀释以0.5EU/ml的鲎试剂检查其热原是可行的。
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| 关 键 词： | 甘油氯化钠注射液 细菌内毒素 鲎试剂 |
| 文章编号： | 1008-7044(2005)06-0438-02 |
| 收稿时间： | 2005-06-30 |
| 修稿时间： | 2005-06-30 |
Study of bacterial endotoxin test for compound glycerin injection |
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| ZHANG Hao,ZHANG Da-ping,LIN Yu-hong,et al.. Study of bacterial endotoxin test for compound glycerin injection[J]. Journal of Huaihai Medicine, 2005, 23(6): 438-439 |
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| Authors: | ZHANG Hao ZHANG Da-ping LIN Yu-hong et al. |
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| Abstract: | Objective To introduce a method to study the bacterial endotoxin test for detecting pyrogen in compound glycerin injection.Methods Limulus reagent was applied to detect pyrogen in compound glycerin injection and interference of compound glycerin injection in the process of bacterial endotoxin test was observed.Results Compound glycerin injection in 2-fold dilution had no interference in the bacterial endotoxin test.[WTHZ]Conclusion Compound glycerin injection in 2-fold dilution applied in 0.5 EU/ml limulus reagent in detection of its pyrogen is feasible. |
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| Keywords: | Compound glycerin injection Bacterial endotoxin Limulus reagent |
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