Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature |
| |
Authors: | Martinez J B Valero J S Bautista A J Restrepo J F Matteson E L Rondon F Iglesias-Gamarra A |
| |
Affiliation: | Internal Medicine and Rheumatology, National University of Colombia, Bogota, Colombia. |
| |
Abstract: | OBJECTIVE: To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies. METHODS: Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies. RESULTS: The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor. CONCLUSION: Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|