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人工反射弧重建膀胱功能动物模型的建立
引用本文:徐瑞生,侯春林,张世民,王金武,王诗波,刘明轩,陈爱民.人工反射弧重建膀胱功能动物模型的建立[J].中国脊柱脊髓杂志,2002,12(2):102-104.
作者姓名:徐瑞生  侯春林  张世民  王金武  王诗波  刘明轩  陈爱民
作者单位:1. 无锡市第三人民医院骨科,214041
2. 第二军医大学长征医院骨科
摘    要:目的 :建立犬“膝腱 脊髓 膀胱”反射弧重建膀胱功能的动物模型 ,作为实验研究人工膀胱反射弧的基础。方法 :家犬 5条 ,行硬膜外L5 S2前根交叉吻接 ,饲养 1年后刺激反射弧并记录膀胱压和尿道压变化。结果 :5只家犬“膝腱 脊髓 膀胱”反射弧均成功建立 ,刺激反射弧时膀胱压和尿道压都有升高。结论 :通过硬膜外L5 S2前根交叉吻接可以更有效地建立人工反射弧重建膀胱功能的动物实验模型。

关 键 词:脊髓损伤  膀胱功能重建  神经再支配  反射弧  
文章编号:1004-406X(2002)-02-0102-03
修稿时间:2001年11月19

An animal model establishment of bladder functional reconstruction with artificial bladder reflex arc
XU Rui sheng,HOU Chun lin,ZHANG Shi min,et al.An animal model establishment of bladder functional reconstruction with artificial bladder reflex arc[J].Chinese Journal of Spine and Spinal Cord,2002,12(2):102-104.
Authors:XU Rui sheng  HOU Chun lin  ZHANG Shi min  
Institution:XU Rui sheng,HOU Chun lin,ZHANG Shi min,et alDepartment of Orthopedic Surgery,Changzheng Hospital,The Second Military Medical University,200003,Shanghai,China
Abstract:Objective:To establish an animal model of bladder functional reconstruction with the "tendon spinal cord bladder" artificial bladder reflex arc.Method: Extrameningeal L5 S2 anterior roots cross anastomosis were performed in 5 dogs and a year latter,the changes of bladder pressure,urethra pressure responded to electrical stimulation on each side were recorded.Result:Artificial bladder reflex arc was established successfully in all 5 dogs and the bladder pressure and urethra pressure were increased while the reflex arc was stimulated.Conclusion:The model of bladder functional reconstruction with artificial bladder reflex arc can be well established by extrameningeal L5 S2 anterior roots cross anastomosis.
Keywords:Spinal cord injury  Bladder functional reconstruction  Reinnervation  Reflex arc  Canine
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