Synaptic Plasma Mèmbrane Antigen D2 Measured in Human Cerebrospinal Fluid by Rocket-Line Immunoelectrophoresis. Determination in Psychiatric and Neurological Patients

The concentration of an antigen partially identical to the rat brain synaptic membrane antigen D2, was measured in human cerebrospinal fluid. The method used was rocket-line immunoelectrophoresis in agarose gel containing the detergent Triton X-100, and line-forming extract of rat brain membranes. No significant differences were found between the controls and patients with multiple sclerosis, inflammatory-degenerative neurological diseases, atrophic brain diseases, acute cerebro-vascular disease, schizophrenia, or affective psychosis.