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12例多囊卵巢综合征患者治疗前后子宫内膜形态改变
引用本文:王俊杰,雷小敏,易慕华.12例多囊卵巢综合征患者治疗前后子宫内膜形态改变[J].重庆医学,2010,39(21).
作者姓名:王俊杰  雷小敏  易慕华
作者单位:三峡大学仁和医院,湖北宜昌,443001;三峡大学仁和医院,湖北宜昌,443001;三峡大学仁和医院,湖北宜昌,443001
基金项目:三峡大学青年科学基金资助项目 
摘    要:目的探讨多囊卵巢综合征(PCOS)患者子宫内膜形态和病理改变及其与性激素和肥胖的关系。方法 12例PCOS不孕患者(PCOS组)经过促排卵治疗后,与7例健康妇女对照组(自然周期)均在着床窗口期观察子宫内膜超声形态学改变,同时取子宫内膜活检观察其病理状态,并研究其与性激素、肥胖的关系。结果 (1)研究对象子宫内膜病理比较:PCOS组间质反应不良和分泌反应欠佳发生率均高于健康对照组,差异有统计学意义(P<0.05)。(2)超声观察着床窗口期子宫内膜厚度,PCOS组略低于健康对照组,但差异无统计学意义(P>0.05);A型内膜出现率,PCOS组低于健康对照组,差异有统计学意义(P<0.05)。结论 PCOS患者子宫内膜的形态和病理均发生了改变,导致子宫内膜容受性缺陷,从而影响胚胎着床。

关 键 词:多囊卵巢综合征  子宫内膜  肥胖指数

Study on endometrium morphologic change before and after treatment in 12 cases of PCOS
WANG Jun-jie,LEI Xiao-min,YI Mu-hua.Study on endometrium morphologic change before and after treatment in 12 cases of PCOS[J].Chongqing Medical Journal,2010,39(21).
Authors:WANG Jun-jie  LEI Xiao-min  YI Mu-hua
Institution:WANG Jun-jie,LEI Xiao-min,YI Mu-hua(Department of Obstetrics , Gynecology,Three Gorges University Renhe Hospital,Yichang 443001,China)
Abstract:Objective To investigate the ultrasonic and pathological characteristics of the endometrium and the relationship with sexual hormones,obesity index in polycystic ovary syndrome(PCOS) patients.Methods Endometrium biopsy was done in the 12 PCOS patients received ovulation induction therapies and the seven nomal women with regular menstruation during implanting window time.then to study the ultra-sonic and pathology features of endometrium.Results(1)Routine HE staining of endometrium:there was significant diff...
Keywords:PCOS  endometrium  obesity index  
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