重型复发性口疮的免疫调整综合疗法

目的研究重型复发性口疮的免疫调整综合疗法的实际效果。方法37例重型复发性口疮接受了免疫调整综合疗法，其中15例合并较重的局部感染、发烧、颌下淋巴结肿大者，采用了静脉点滴大剂量抗生素，结合免疫调整综合治疗。22例局部感染较轻，体温正常者采用了中等剂量抗生素静滴，结合免疫调整综合治疗。免疫调整主要应用胸腺肽及大剂量肾上腺皮质激素逐渐减量疗法，以及大剂量V．C．、B6叶酸疗法。综合治疗侧重于多种维生素疗法及高营养疗法，以及饮食指导。结果37例重症复发性口疮经治一周，溃疡愈合，经5—8周巩固治疗嘱定期复查，随访三年未见复发。结论重型复发性口疮免疫调整综合治疗方法，疗效可靠，如能坚持巩固治疗，可以防止复发。

Immunologic Regulate Complex Therapy for Seriously recurrent Ulcer of Mouth

Objective To study on the effect of Immunologic regulate complex therapy for seriously recurrent ulcer of mouth. Methods 37 patients with seriously recurrent ulcer of mouth adapted immunologic regulate complex therapy： within 15 cases had sriously local infection, swelling of submandibular hymph nodes with fever, adopted large doses of antibiotic in venous transfusion compounded Immunologic regulate complex therarpy. The 22 patients with less local infection and have normal tempelatare accepted a middling doses antibiotic through in nenous compound immunologic negulate complex therapy. The immunologic regulate compler theratY are mainly accepted thymopeptides treatmentl and large doses of adrenl cortical hormon （in first week）. Then gladually reduce of doses of treatment methods, and take a large dases of V.C. VB6 fori acid. The complex therapy are mainly vitamins with minerals Tablets （21） treatment, high nourishment treatment and nourishment of directions by doctor. Results 37 patients with seriously recurrent ulcer of mouth, according above mentioned methods treated, the ulcec had cured in the one week through 5-8 weeks strenthen treatmen then finished the treatment course this group 37 patients fallow up 3 years had not seen relaps, eonclusion Immunologic regulate cmplex therapy ot seriously recurrent ulcer of mouth are good effect, if could be to insist strenthen treatment course may be prevent the relapse.