Pertussis and respiratory syncytial virus infections |
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| Authors: | Cécile Cosnes-Lambe Josette Raymond Martin Chalumeau Charlotte Pons-Catalano Florence Moulin Nathalie de Suremain Hélène Reglier-Poupet Pierre Lebon Claire Poyart Dominique Gendrel |
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| Affiliation: | 1.Department of Pediatric and Emergency,Université Paris 5, APHP, H?pital Saint Vincent de Paul-Cochin,Paris,France;2.Microbiology Unit,Université Paris 5, APHP, H?pital Saint Vincent de Paul-Cochin,Paris,France;3.Hopital Saint Vincent de Paul,Paris,France |
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| Abstract: | During the winter 2005-2006, all infants <4 months of age admitted for bronchiolitis or acute respiratory tract infection in a tertiary care pediatric hospital in Paris were tested for respiratory syncytial virus (RSV) and pertussis with real-time polymerase-chain reaction (RT-PCR). A positive pertussis-PCR was found in 14/90 (16%) infants infected with RSV and in 5/30 negative for RSV. Similar clinical symptoms were found in all RSV-positive infants with or without pertussis co-infection. Most infants (73%) were not vaccinated against pertussis, and the other children had received one or two injections. In conclusion, pertussis-RSV co-infection is common in young infants, and pertussis-PCR should be used, whenever available. |
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| Keywords: | Pertussis RSV coinfection Infants |
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