维持性血液透析患者心脏瓣膜钙化与血脂异常的关系

目的 探讨维持性血液透析（MHD）患者心脏瓣膜钙化与血脂代谢紊乱的关系.方法 菲利普IU33 彩色多普勒超声诊断仪检测80 例患者心脏瓣膜钙化情况,将患者分为钙化组（18 例）和对照组（62 例）,比较两组患者血红蛋白、血清白蛋白、血脂、心脏结构等指标.结果 钙化组年龄及透析龄高于对照组（P 〈0.01）,左房扩大及左心室舒张功能减退（LVDD）发生率高于对照组（P 〈0.01）;总胆固醇（TC）、低密度脂蛋白胆固醇（LDL C）、载脂蛋白B（Apo B）均高于对照组.结论 维持性血液透析患者心脏瓣膜钙化与年龄、透析龄、血脂异常有关,易发生心脏结构异常.

Re lationship betw een C ardiac Valve C alcification and Dyslipidem ia in M aintenance Hem odylisis

Objective To explore the relationship between cardiac valve calcification and blood lipid metabolic disorder in pa- tients with maintenance hemodialysis.Methods The valve calcification was assessed using Philip IU33 color Doppler ultrasonogra- phy in 80 patients.All patients were divided into two groups：Calcification group（n= 18）and control group （n = 62）.Hemoglobin,ser- um albumin,serum lipid and heart structure were compared between two groups.Results Age and duration of dialysis were longer incalcification group.In calcification group,incidence of left atrial enlargement and LVDD,the level of TC,LDL C,Apo B were higherthan that in control group.Conclusion Cardiac valve calcification in patients with maintenance hemodialysis were closely related toage,duration of dialysis,dyslipidemia,prone to heart structural abnormalities.