| 脂肪源性干细胞研究及其应用进展 |
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| 引用本文： | Nie X,Chen H,Tang N,Bian K. 脂肪源性干细胞研究及其应用进展[J]. 中国修复重建外科杂志, 2011, 25(7): 854-858 |
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| 作者姓名： | Nie X Chen H Tang N Bian K |
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| 作者单位： | 上海中医药大学穆拉德中药现代化研究中心;浙江大学医学院附属二院干部保健科;上海市教委高校一氧化氮与炎症医学E-研究院;美国德克萨斯大学休斯敦医学院综合生物及药理学系;德克萨斯大学分子医学研究所; |
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| 基金项目： | 国家科技部“十一五”支撑计划资助项目(2006BAIⅡB08-03); 上海市教委高校一氧化氮与炎症医学E-研究院计划项目(E-04010); 上海市科委基础研究重点项目(08430711300、08DZ1972104); 国家科技部重大专项重大新药创制项目(2009ZX09311-003)~~ |
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| 摘 要： | 目的对脂肪源性干细胞(adipose-derived stem cells,ADSCs)的生化特征、应用进展及前景等进行综述。方法广泛查阅近年关于ADSCs的实验研究及临床研究文献,并进行整理、综合与分析。结果 ADSCs取材方便,易于培养,分化潜能巨大,可在体外稳定增殖传代。ADSCs在动物实验和临床应用中均取得重大进步,已广泛应用于临床进行心血管疾病、代谢性疾病、脑病的治疗及组织工程修复。结论 ADSCs逐渐取代了BMSCs,已成为干细胞研究的重点和热点。
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| 关 键 词： | 脂肪源性干细胞 再生医学 组织工程 |
Research and application progress of adipose-derived stem cells |
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| Nie Xuqiang,Chen Huaihong,Tang Ning,Bian Ka. Research and application progress of adipose-derived stem cells[J]. Chinese journal of reparative and reconstructive surgery, 2011, 25(7): 854-858 |
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| Authors: | Nie Xuqiang Chen Huaihong Tang Ning Bian Ka |
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| Affiliation: | 1,3,4.1Murad Research Center for Modernized Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai,201203,P.R.China;2Department of Cadres Healthcare,the 2nd Aff iliated Hospital of Zhejiang University School of Medicine;3E-Institute of Shanghai Universities,Division of Nitric Oxide and In? ammatory Medicine;4Department of Integrative Biology and Pharmacology,Institute of Molecular Medicine,University of Texas Medical School. |
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| Abstract: | Objective To review the biochemical characteristics,application progress,and prospects of the adipose-derived stem cells(ADSCs).Methods The recent original experimental and clinical literature about ADSCs was extensively reviewed and analyzed.Results ADSCs can be readily harvested in large numbers from adipose tissue with properties of stable proliferation and potential differentiation in vitro.Significant progress of ADSCs is made in the animal experiment and the clinical application.It has been widely use... |
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| Keywords: | Adipose-derived stem cells Regenerative medicine Tissue engineering |
| 本文献已被 CNKI PubMed 等数据库收录！ |
