| 基于反卷积方法的脑激活定位分析 |
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| 引用本文： | 尹东,赵晓军. 基于反卷积方法的脑激活定位分析[J]. 北京生物医学工程, 2002, 21(3): 169-170. DOI: 10.3969/j.issn.1002-3208.2002.03.003 |
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| 作者姓名： | 尹东 赵晓军 |
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| 作者单位： | 中国科学技术大学信息处理中心,合肥,230027 |
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| 摘 要： | 目前用fMRI进行脑功能研究的主要依据是血流敏感性[1]和BOLD[2](blood oxygenation-level dependent)对比度增强原理.当某一脑区被激活时,由于血流增加,引起了氧合血红蛋白浓度的瞬态增加,导致磁化率加权脉冲序列中MR信号的增强.本文着重讨论了反卷积方法在脑激活定位中的应用.该法可以有效地提供良好的解剖学定位,为进一步实现被试间图像的比较分析或由多个被试提取一般性的脑活动机理做准备.
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| 关 键 词： | 脑功能 功能磁共振成像 信号检测 图像处理 卷积 |
| 文章编号： | 1002-3208(2002)03-0169-02 |
| 修稿时间： | 2001-10-17 |
Location Analysis of Brain Activation Based on Method of Inverse Convolution |
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| YIN Dong,ZHAO Xiaojun. Information Processing Center of USTC,Hefei. Location Analysis of Brain Activation Based on Method of Inverse Convolution[J]. Beijing Biomedical Engineering, 2002, 21(3): 169-170. DOI: 10.3969/j.issn.1002-3208.2002.03.003 |
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| Authors: | YIN Dong ZHAO Xiaojun. Information Processing Center of USTC Hefei |
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| Affiliation: | YIN Dong,ZHAO Xiaojun. Information Processing Center of USTC,Hefei 230027 |
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| Abstract: | At present, the main basis of brain function research using fMRI is blood flow sensitivity and principle of contrast enhancement of BOLD(blood oxygenation level dependent). When activating a brain area, due to blood flow increase. There was transient increase of concentration of oxy hemoglobin, causing enhancement of MR signals in magnetic susceptibility weighted pulse series. We mainly focus on discussion of the application of inverse convolution method for the brain activation location. This method could provide good anatomia location effectively so as to lay foundation for comparison and analysis of tested images, or for study of mechanism of several general brain activities to be tested. |
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| Keywords: | Brain function fMRI Signal detection Image processing Convolution |
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