极低出生体质量儿应用持续喂养或间断喂养的 meta 分析

目的评价持续喂养及间断弹丸式注射两种喂养方式在极低出生体质量儿的不同影响。方法应用continuous、intermittent bolus、nasogastric、premature、very low birth weight等关键词检索Pubmed、EMBASE、Ovid、the Cochrane Library和中国生物医学文献数据库发表的文章,并同时检索相关的参考文献,对资料进行meta分析。结果不同国家的7项研究被纳入。病例数共434例,其中使用持续鼻胃管喂养者217例,间断鼻胃管注射者217例,分析发现两种喂养方式对极低出生体质量儿的影响差异无统计学意义。结论在热卡足够的前提下,选择何种喂养方式均不会对极低出生体质量儿产生明显的影响。

Meta analysis of continuous versus intermittent feeding in very low birth weight infants

Objective To compare the effects of continuous versus intermittent feedings on the growth of very low birth weight infants. Methods Databases of Pubmed,Embase,Ovid,the Cochrane library and CBM were searched through internet,and citations of relevant original studies were also searched manually by using keywords of 'ontinuous,intermittent,nasogastric,premature,very low birth weight' Meta analysis was done on the results of these studies. Results Seven eligible studies with 434 infants were identified,among them,217 were fed using continuous nasogastric gavage,and other 217 were fed by intermittent nasogastric gavage. The result of the Meta analysis revealed that there was no statistical difference in the growth of the infants between two feeding methods. Conclusions Feeding methods are associated with similar outcomes when calorie intake is guaranteed.