| 组织工程人工骨材料修复长骨节段性缺损的现状与展望 |
| |
| 引用本文： | 李长庚,徐建强.组织工程人工骨材料修复长骨节段性缺损的现状与展望[J].中国组织工程研究与临床康复,2011,15(25). |
| |
| 作者姓名： | 李长庚 徐建强 |
| |
| 作者单位： | 解放军第二炮兵总医院骨科,北京市,100088 |
| |
| 基金项目： | 全军医药卫生科研基金课题 |
| |
| 摘 要： | 背景:骨移植、人工替代物置换、骨延长等长骨节段性缺损修复方法虽已在临床上应用,但均有各自的局限性.目的:就目前骨缺损的治疗加以回顾总结,并对长骨大段性缺损的修复方式作展望性分析.方法:由第一作者检索PubMed数据库、中文生物医学文献期刊数据库2000-01/2010-12有关长骨大段性缺损修复的文章.英文关键词为"bone defect,bone tissue engineering,artificial bone,bone transplantation,therapy",中文关键词为"骨缺损,骨组织工程,人工骨,骨移植,治疗".排除标准陈旧性文章及重复性研究.结果与结论:保留33篇文献进行文献证据提取.长骨节段性缺损的治疗包括自体骨移植、异体骨移植、骨延长、人工骨替代移植等,以组织工程人工骨的研究、利用为热点和主要发展方向,但以基础性研究和动物实验为多,少见于临床应用.组织工程人工骨在应用于临床长骨缺损治疗之前,尚存诸多问题急需解决,但仍为最有开发前景的骨缺损修复材料.
|
| 关 键 词： | 长骨节段性缺损 修复 生物材料 骨组织工程 人工骨 骨移植 |
Tissue-engineered bone materials for repair of long bone segmental defects |
| |
| Li Chang-geng,Xu Jian-qiang.Tissue-engineered bone materials for repair of long bone segmental defects[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(25). |
| |
| Authors: | Li Chang-geng Xu Jian-qiang |
| |
| Institution: | Li Chang-geng,Xu Jian-qiang Department of Orthopedics,General Hospital of the Second Artillery Force of Chinese PLA,Beijing 100088,China |
| |
| Abstract: | BACKGROUND:Bone graft,artificial substitute replacement,bone lengthening and other repair methods for long bone segmental defects have been used in clinic,but they have their own limitations.OBJECTIVE:To review and summarize the current methods of bone defect treatment,and to analyze the developmental prospect of the treatment for the long bone defect.METHODS:The first author searched PubMed Database and Chinese Medical Current Contents to retrieve articles about long bone defect repair published 2000-01 to... |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
