| 青蒿素体外抑制胆囊癌细胞生长作用的研究 |
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| 引用本文： | 董戬,贺强,赵浩亮.青蒿素体外抑制胆囊癌细胞生长作用的研究[J].中国医疗前沿,2010,5(23):1-2. |
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| 作者姓名： | 董戬 贺强 赵浩亮 |
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| 作者单位： | 董戬,贺强,DONG Jian,HE Qiang(山西医科大学研究生学院普外科,太原,030001);赵浩亮,ZHAO Hao-liang(山西医科大学第一临床医学院普外科) |
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| 摘 要： | 目的观察青蒿素（ART）对人胆囊癌细胞的抑制作用。方法以不同浓度的青蒿素在不同时间内作用于体外培养的人胆囊癌（GBC-SD）细胞,采用四甲基偶氮唑盐比色法（MTT）检测细胞生长抑制率,应用流式细胞仪检测细胞凋亡情况。结果青蒿素可显著抑制GBC-SD细胞生长,诱导细胞发生凋亡,并呈一定的量-效、时间-效应关系。结论青蒿素对体外培养的GBC-SD细胞有明显的抑制作用。
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| 关 键 词： | 青蒿素 抗肿瘤作用 人胆囊癌细胞 实验研究 |
Research of the effect of Artemisinin inhibition on the cells of gallbladder |
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| DONG Jian,HE Qiang,ZHAO Hao-liang.Research of the effect of Artemisinin inhibition on the cells of gallbladder[J].China Healthcare Innovation,2010,5(23):1-2. |
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| Authors: | DONG Jian HE Qiang ZHAO Hao-liang |
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| Institution: | DONG Jian,HE Qiang,ZHAO Hao-liang.Shanxi Medical University,Taiyuan 030001,China |
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| Abstract: | Objective Study the effect of Artemisinin inhibition on the cells of gallbladder(GBC-SD).Methods The cultured GBC-SD cells were treated with different concetrations of Artemisinin and different incubation time.MTT was used to detect the cell growth inhibition rate,and flow cytometry was used to study the cell apoptosis.Result Artemisinin significantly inhibits the growth of GBC-SD cells,inducing apoptosis.And showed some dose-time-effect relationship.Conclusion Artemisinin has obvious inhibition effect on G... |
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| Keywords: | Artemisinin Neoplasms GBC-SD Experimental study |
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