86例新生儿缺氧缺血性脑病的围生期因素临床分析

目的:探讨新生儿缺氧缺血性脑病(HIE)的围生期相关危险因素及预防措施。方法:回顾性分析86例新生儿缺氧缺血性脑痛的儿科临床资料。结果:胎儿宫内窘迫与新生儿窒息是HIE发病的最主要原因,产前、产时高危因素占94.2%。胎儿宫内窘迫、新生儿窒息、5分钟Apgar评分、低体重是影响HIE临床分度的重要因素。结论:对高危孕妇产前要进行严密监测,及时评估高危因素并适时终止妊娠;产时出现窒息,积极有效的新生儿复苏技术是预防HIE的关键,不能单纯以Apgar评分来判断新生儿脑缺氧的发生,加强高危儿的监护。

Analysis of perinatal factors of 86 Cases of hypoxic-ischemic encephalopathy

Objective：To explore the related risk factors and preventive measures of hypoxic-ischemic en- cephalopathy （HIE） in the perinatal period. Methods：Retrospective analysis into the pediatric clinical material of 86 cases of HIE. Results：The most main reason of HIE was fetal distress and neonatal asphyxia, prenatal and intrapartum risk factors accounted for 94.2%. Fetal distress, neonatal asphyxia, 5 rain Apgar score and low birth weight made a notable impact on the Clinical grading of HIE.Conclusion：It is necessary to undertake close monitor, timely risk factors evaluation and timely end pregnancy for high risk pregnant women; Positive and effective neonatal resuscitation tech- nology is the key to prevention of HIE when asphyxia appears in childbirth. It is improper to determine the occurrence of neonatal cerebral anoxia by only depending on Apgar score. It is of great significance to strengthen the monitoring of high-risk neonatus