实时三维超声心动图定量评价左室容积模型的实验研究

目的探讨实时三维超声心动图(RT-3DE)全容积成像及双平面法测量左心室容积的可行性和准确性。方法应用RT-3DE采集22个左室模型(包括10个近正常心脏模型,12个室壁瘤模型,53~292ml)的双平面图像和全容积数据,启动PhilipsQLab分析软件,计算水囊容积。同时与2DESimpson法测量值和实际注水量进行比较。结果在10个正常左室模型中,全容积成像、双平面法与二维超声测值与实际容积值相关性良好,有高度一致性;12个不规则室壁瘤模型中,双平面法及全容积成像测值与实际容积值间相关良好,无显著差异,一致性好;而2DE测值与实际容积值间差异显著(P<0.05),一致性较差。结论实时三维双平面法和全容积成像法测量左室容积较二维法准确,且双平面法便捷,全容积法更准确。其为准确、快速、简便地评价左心室几何容积和功能提供了新的有力工具。

Quantitation of the volume of left ventricular models by real-time three-dimensional echocardiography: experimental study

Objective To evaluate the feasibility and accuracy of real-time three-dimensional echocardiography (RT-3DE) full volume and X-plane for quantifying the volume of left ventricular (LV) models. Methods Twenty-two different rubber bursas (include 10 normal LV models and 12 irregular LV aneurysm models, 53-292 ml) were quantified by RT-3DE full volume and X-plane respectively. The volumes were calculated using Philips iE33 3DQ Advance software online, which compared with 2DE (measured by Simpson method) and true volume (measured by drained water) using correlation analysis and Bland-Altman methods. Results In the 10 normal LV models, excellent correlation coefficients and low variability were observed between the three methods and the true volumes. In the 12 LV aneurysm models, excellent correlation coefficients and low variability were observed in the volumes measured by RT-3DE full volume and X-plane, there was no significant difference between the two methods and the true volumes. However, there was difference between 2DE and true volume (P<0.05), and the consistency was not acceptable. Conclusion Comparing with 2DE, RT-3DE full volume and X-plane can quantify LV volumes accurately, X-plane was more rapidly, and full volume was more accurate, which provide a new method for quantifying LV geometric volume and function accurately, conveniently and rapidly.