基于累积缺陷原则构建的衰弱指数及其应用进展

衰弱是因机体生理储备和应激适应能力下降和失调而易发生不良结局的临床状态或综合征。目前衰弱的评估无金标准，但研究发现累积缺陷模型对各种不良临床事件的预测能力高于其他衰弱评估方法。本文主要对基于累积缺陷原则构建的衰弱指数及其构建方法、常见种类及其应用等方面相关研究进行综述，为衰弱评估提供新思路和新方法。

Frailty index model based on cumulative defect principle and its application

railty is a clinical state or syndrome that is prone to adverse health outcomes due to the decline of physiological reserve and stress adaptability of the elderly. Here is no gold standard for the assessment of frailty, but the cumulative defect model has been found to be better at predicting various adverse clinical events than other frailty assessment methods. This paper summarized the relevant research from the frailty index based on the principle of cumulative defects and its construction methods, common types and applications, so as to further improve the clinical doctors'' understanding of the frailty index model based on the principle of cumulative defects, and provide new ideas and methods for frailty evaluation.