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注射用更昔洛韦与木糖醇注射液配伍的稳定性研究
引用本文:谢冬梅,王群,邢蓉.注射用更昔洛韦与木糖醇注射液配伍的稳定性研究[J].中国现代药物应用,2011,5(4):10-11.
作者姓名:谢冬梅  王群  邢蓉
作者单位:安徽省蚌埠医学院第一附属医院药剂科,230061
摘    要:目的考察注射用更昔洛韦与木糖醇注射液配伍的稳定性。方法采用紫外分光光度法测定并考察注射用更昔洛韦与木糖醇注射液配伍后室温(25℃)下3 h内更昔洛韦的质量浓度、外观及PH值的变化。结果 3 h内,注射用更昔洛韦在木糖醇注射液中含量、颜色及PH值无显著变化。结论注射用更昔洛韦与木糖醇注射液在配伍3 h内是稳定的。

关 键 词:注射用更昔洛韦  配伍稳定性  木糖醇

Study on the compatible stability of Ganciclovir for Injection in xylItol solution
XIE Dong-mei,WANG Qun,XING Rong.Study on the compatible stability of Ganciclovir for Injection in xylItol solution[J].Chinese Journal of Modern Drug Application,2011,5(4):10-11.
Authors:XIE Dong-mei  WANG Qun  XING Rong
Institution:.Department of Pharmacy,The First Affiliated Hospital of Bengbu Medical,Benbu,Anhui province,233004,China
Abstract:Objective To study the stability of Ganciclovir for Injection in xylItol solution.Methods By using ultraviolet spectrophotometry,the contents of Ganciclovir for injection in xylItol solution was determined and the external appearance and PH value were observed after Ganciclovir for injection and xylItol solution were mixed at room temperature(25℃) within three hours.Results No obvious variations were found in the content of Ganciclovir in xylItol solutions,the color and the PH value within 3 hours.Conclusion It is stable when Ganciclovir for injection is mixed with xylItol solutions within 4 hours.
Keywords:Ganciclovir for injection  Compatible stability  XylItol
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