胃肠道非霍奇金淋巴瘤的治疗

目的：探讨原发于胃肠道的恶性淋巴瘤（Primary Gastrointestinal Malignant Lymphoma PGIML)治疗方式与疗效的关系。方法：回顾性分析我院1981年5月－1997年5月治疗的52例PGIML的资料，将其分为单纯手术（单术）、手术＋化疗（术化）及手术＋放疗＋化疗（综合）三个组，以kaplan-Meier方法分别统计其1、3、5年生存率，Logrank作显著性检验。结果：单术、术化及综合组实际5年生存率分别为20．0％、60．8％及78．5％，与单术相比有显著性意义（P＜0．05），尤以综合组的疗效最好。说明在PGIML治疗中，放疗是一种有效的手段。结论：PGIML治疗宜采用手术配合放、化疗的综合治疗。

Analysis of the relationship between primary gastrointestinal malignant lymphoma therapeutic methods and the effects

Objective To evaluate the relationship between therapeutic methods and effects on primary gastrointestinal malignant lymphoma (PGIML). Methods From May 1981 to May 1997, fifty-two PGIML patients who were divided into three groups: operation alone (OA), surgery combined with chemotherapy (SC). and surgery combined radiotherapy and chemotherapy (SRC). These cases were analyzed retrospectively. The 1-3 and 5-year survival rates were statistically calculated by Kaplan Meier method and multiple factor Log-rank test. Results The 5year survival rates of OA. SC and SRC were 20.0%?60.8% and 78.5% respectively. There were significant differences comparing with OA. Especially, SCR group was more significant. The optimal effective treatment was SCR group. It shows that radiotherapy is one of effective treatment methods for PGIML. Conclusion Surgery combined with radiotherapy and chemotherapy is a suitable method for the treatment of PGIML.