两种方案治疗急性冠周炎的成本-效果分析

目的探讨甲硝唑和奥硝唑两种方案治疗急性冠周炎的成本-效果。方法将96例急性冠周炎患者随机均分为两组，甲组予奥硝唑片0．5g，2次／d，口服，乙组予甲硝唑片0．2g，3次／d,口服，两组均用3％双氧水和生理盐水交替冲洗盲袋，1次／d，进行7d的疗效观察和不良反应观察，并采用成本-效果分析方法进行评价。结果甲组和乙组总成本分剐为93．80元和35．61元，总有效率分别为91．67％和60．42％，不良反应发生率分别为12．5％和27．1％。结论甲组成本高，疗效好，乙组成本虽低，但疗效也差；不良反应发生率乙组明显高于甲组。成本-效果分析表明。奥硝唑治疗急性冠周炎明显优于甲硝唑。

Cost-effect Analysis on Two Treatment Schemes of Acute Pericoronitis

Objective To discuss the cost- effect of two schemes in treating acute pericoronitis. Methods 96 patients with acute pericoronitis were divided into two groups. Group A was given oral Ornidazole Tablets 0.5 g, b. i. d, and group B was given oral metronidazole tablets 0.2 g, t. i. d. The blind sack in group A and group B was cleaned with 3% H2O2 and physiological saline in turn, once daily. The curative effect and adverse reactions were investigated and evaluated by the cost- effect method after 7 d of treatment. Results The total costs of group A and group B were RMB 93.80 and 35.61 respectively. The general effective rates were 91.67% and 60.42% respectively, Conclusion The cost in group A is higher than group B, but the curative effects is better than it. Group B has more adverse reactions compared with group A. Ornidazole is superior to metronidazole in treating acute pericoronitis.