| Dual Effect of 3, 4- Dihydroxyacetophenone on LPS-induced Apoptosis in RAW264.7 Cells by Modulating the Production of TNF-α |
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| 作者姓名： | 吴萍 叶笃筠 张代娟 张力 万敬员 盘茜 |
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| 作者单位： | Department of Pathophysiology，Tongji Medical College，Huazhong Science and Technology University，Wuhan 430030，China，Department of Pathophysiology，Tongji Medical College，Huazhong Science and Technology University，Wuhan 430030，China，Department of Pathophysiology，Tongji Medical College，Huazhong Science and Technology University，Wuhan 430030，China，Department of Pathophysiology，Tongji Medical College，Huazhong Science and Technology University，Wuhan 430030，China，Department of Pathophysiology，Tongji Medical College，Huazhong Science and Technology University，Wuhan 430030，China，Department of Pathophysiology，Tongji Medical College，Huazhong Science and Technology University，Wuhan 430030，China |
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| 基金项目： | This project was supported by grants of the National Natu ral Scientific Foundation of China (No. 30070929) and (No.30100226). |
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| 摘 要： | 3, 4 dihydroxyacetophenone ( DHAP) is anactive component isolated from leaves of Tuma odongqing ( Ilex Pubescens Hook. Et Arn. Varglaber Chang), a Chinese traditional herb. It is in itially used to promote blood circulation and re move blood stasis[1, 2]. Previous experimental andclinical data proved that it could regulate the bal ance between TXA2 and PGI2, cause vesodilationand inhibit platelet aggregation[3]. It has showed agood curative effect in the…
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| 关 键 词： | dihydroxyacetophenone apoptosis macrophage TNF-α NF-κB inflammation |
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