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吐温-80对大鼠心血管系统作用的影响
引用本文:王宁,周远大,杨辉,何海霞. 吐温-80对大鼠心血管系统作用的影响[J]. 中国药房, 2004, 15(5): 273-275
作者姓名:王宁  周远大  杨辉  何海霞
作者单位:1. 重庆医科大学附属第一医院药剂科,重庆市,400016
2. 重庆医科大学附属第一医院临床药理基地,重庆市,400016
摘    要:目的 :探讨吐温 -80对心血管系统的影响。方法 :观察不同浓度吐温 -80静脉注射后对大鼠心血管系统的影响。结果 :静脉注射吐温 -80量大时即可出现心血管系统抑制现象 ,小剂量吐温 -80未见对心血管系统产生明显影响。结论 :临床输注含吐温 -80制剂时应控制速度或剂量。

关 键 词:吐温-80  大鼠  心血管系统
文章编号:1001-0408(2004)05-0273-03
修稿时间:2004-01-15

Effect of Tween 80 on Cardiovascular System in Rats
WANG NingDept.of Pharmacy,The First Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing ZHOU Yuanda,YANG Hui,HE HaixiaBasis of Clinical Pharmacology,The First Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing. Effect of Tween 80 on Cardiovascular System in Rats[J]. China Pharmacy, 2004, 15(5): 273-275
Authors:WANG NingDept.of Pharmacy  The First Affiliated Hospital of Chongqing University of Medical Sciences  Chongqing ZHOU Yuanda  YANG Hui  HE HaixiaBasis of Clinical Pharmacology  The First Affiliated Hospital of Chongqing University of Medical Sciences  Chongqing
Affiliation:WANG NingDept.of Pharmacy,The First Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing400016 ZHOU Yuanda,YANG Hui,HE HaixiaBasis of Clinical Pharmacology,The First Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing400016
Abstract:OBJECTIVE:To study the effect of Tween80on cardiovascular system.METHODS:To observe the effects of Tween80in different concentrations i.v.on cardiovabcular system in rats.RESULTS:In high-dose of Tween80i.v.,inhibi_ ting effect on cardiovascular system appeared,while no inhibiting effect occured in low-dose of Tween80.CONCLUSION:The rate and dose of Tween80in intravenous infusion should be under control in clinical practice.
Keywords:Tween80  rat  cardiovascular system
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