脑出血恢复期内分泌激素异常的研究

目的 探讨脑出血恢复期患者内分泌激素变化情况.方法 用放射免疫法测定90例脑出血患者发病后3个月,6个月,12个月周围静脉血中FT3、FT4、TSH、GH、ACTH、Cor、PRL、T、E2、FSH、LH、P的浓度.分析内分泌异常的发生率及其与出血量、有无并发症及恢复时间的关系.结果 内分泌激素异常在发病后3个月时发生率11.1％,6个月时发生率8.9％,12个月时发生率7.8％.随着恢复时间的延长逐渐下降,出血量越大分泌异常发生率越高,发病当时有并发症者恢复期内分泌激素异常发病率高.结论 脑出血恢复期内分泌异常有一定的发生率,有必要对恢复期患者进行常规的内分泌激素水平检查,并用于指导治疗.

Investigation of the incidence of hormone abnormality in the convalescence stage of cerebral hemorrhage

Objective To investigate the incidence of hormone abnormality in the convalescence stage of cerebral hemorrhage.Methods The concentration of FT3, FT4, TSH, GH, ACTH, Cor, PRL, T, E2, FSH, LH, P in peripheral blood were measured by radioimmunoassay at 3, 6, 12 months after hemorrhage.Analysis the incidence of the abnormal neuroendocrine hormone and its relation to the blood volume, complications and recovery time.Results Neuroendocrine hormone abnormalities occur rate at 3 months was 11.1%, 6 months was 8.9%, 12 months was 7.8%.Hormone abnormality rate was reduced with the recovery time and positively related to the blood volume.The incidence of hormone abnormalities in patients had complications was higher than the non-complications.Conclusions In the recovery phase, some patients with cerebral hemorrhage have neuroendocrine hormone abnormalities.The hormone levels can be used as a important index to guide clinical therapy.