| 润通丸质量标准研究 |
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| 引用本文： | 唐亮,王小青.润通丸质量标准研究[J].解放军药学学报,2008,24(2):151-153. |
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| 作者姓名： | 唐亮 王小青 |
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| 作者单位： | 1. 解放军总医院第一附属医院,北京,100037
2. 军事医学科学院,北京,100850 |
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| 摘 要： | 目的建立润通丸的质量标准。方法采用TLC法对润通丸中的白芍、枳实、大黄进行定性鉴别；用高效液相色谱法测定该制剂中芍药苷的含量。结果薄层色谱法可明显鉴别出该制剂中的白芍、枳实、大黄。芍药苷在0．2-1．6μg范围内，进样量与峰面积线性关系良好，r=0．9999，样品的平均加样回收率为99．45％，RSD为0．73％，n=9。结论薄层色谱法呈现斑点清晰，专属性强，可用于润通丸的鉴别；高效液相色谱法简便快速，精密度高，准确度好，可用于该制剂的质量控制。
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| 关 键 词： | 润通丸 TLC HPLC 芍药苷 |
| 文章编号： | 1008-9926(2008)02-0151-03 |
| 修稿时间： | 2007年11月21 |
Study on Quality of Runtong Pills |
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| TANG Liang,WANG Xiao-Qin.Study on Quality of Runtong Pills[J].Pharmaceutical Journal of Chinese People's Liberation Army,2008,24(2):151-153. |
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| Authors: | TANG Liang WANG Xiao-Qin |
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| Institution: | TANG Liang, WANG Xiao-Qin (Department of Pharmacy,The First Affiliated Hospital of General Hospital of PLA,Beijing 100037 China;Academy of Military Medical Sciences, Beijing 100850 China) |
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| Abstract: | Aim To establish a quality standard for Runtong Pills. Methods Radix paeoniae alba, fructus aruantii immaturus, radix et rhizome rhei were identified by TLC, and the contents of paeoniflorin in Runtong Pills were determined by HPLC. Results TLC can clearly identify the radix paeoniae alba, radix et rhizoma rhei and fructus aurantii immaturus of this Chinese herbal preparation. Paeoniflorin showed a good linear relationship within a range of 0.2 - 1.6μg, r = 0.999 9 ; the average recovery was 99.45%, RSD = 0.73%, n = 9. Conclusion In TLC, the spots are clear and specific enough to identify the herbal medicine in Runtong Pills. It is simple, quick, highly precise for HPLC to control the quality of Runtong Pills. |
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| Keywords: | Runtong Pills TLC HPLC Paeoniflorin |
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