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Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A
Authors:Janan Mohamad  Ofer Sarig  Lisa M. Godsel  Alon Peled  Natalia Malchin  Ron Bochner  Dan Vodo  Tom Rabinowitz  Mor Pavlovsky  Shahar Taiber  Maya Fried  Marina Eskin-Schwartz  Siwar Assi  Noam Shomron  Jouni Uitto  Jennifer L. Koetsier  Reuven Bergman  Kathleen J. Green  Eli Sprecher
Affiliation:1. Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;2. Department of Human Molecular Genetics & Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;3. Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA;4. Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;5. Research Center for Digestive Disease, Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv, Israel;6. Variantyx, Ltd, Framingham, Massachusetts, USA;7. Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA;8. Department of Dermatology, Rambam Health Care Campus, Haifa, Israel;9. Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel;10. Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Abstract:
Keywords:CDSN  corneodesmosin  PSS  peeling skin syndrome  siRNA  small interference RNA
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