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Population-level surgical outcomes for infantile hypertrophic pyloric stenosis
Authors:Nick Lansdale  Nadeem Al-Khafaji  Patrick Green  Simon E Kenny
Institution:1. Alder Hey Children''s Hospital, Liverpool, UK;2. University of Liverpool, Liverpool, UK
Abstract:

Objectives

Determine national outcomes for pyloromyotomy; how these are affected by: (i) surgical approach (open/laparoscopic), or (ii) centre type/volume and establish potential benchmarks of quality.

Methods

Hospital Episode Statistics data were analysed for admissions 2002–2011. Data presented as median (IQR).

Results

9686 infants underwent pyloromyotomy (83% male). Surgery was performed in 22 specialist (SpCen) and 39 nonspecialist centres (NonSpCen). The proportion treated in SpCen increased linearly by 0.4%/year (r = 0.76, p = 0.01). Annual case volume in SpCen vs. NonSpCen was 40 (24–53) vs. 1 (0–3). Time to surgery was shorter in SpCen (1 day 1, 2] vs. 2 1–3]), but total stay equal (4 days 3–6]). 137 (1.4%) had complications requiring reoperation (wound problem 0.6%; repeat pyloromyotomy 0.5% and perforation, bleeding or obstruction 0.2%): pooled rates were similar between SpCen and NonSpCen (1.4% vs. 1.6%, p = 0.52). Three NonSpCen had > 5% reoperations (within 99.8% C.I. as small denominators). There was no relationship between reoperation and centre volume. Laparoscopic pyloromyotomy had increased risk of repeat pyloromyotomy (OR 2.28 1.14–4.57], p = 0.029).

Conclusions

Pyloric stenosis surgery shifted from centres local to patients, but outcomes were unaffected by centre type/volume. Modest reported benefits of laparoscopy appear offset by increased reoperations. Quality benchmarks could be set for reoperation < 4%.

Type of study

Treatment Study.

Level of evidence

Level III.
Keywords:PS  pyloric stenosis  RCT  randomised controlled trial  SpCen  specialist centres  NonSpCen  nonspecialist centres  DGH  district general hospital  HES  Hospital Episode Statistics  Pyloric stenosis  Outcomes  Pyloromyotomy  Hospital episode statistics  Volume-outcome  Infant
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