| Using PEG as Progen to Preparate Chitosan Scaffold for Tissue Engineering |
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| 引用本文： | Li Qin-hua Chen Jian-su. Using PEG as Progen to Preparate Chitosan Scaffold for Tissue Engineering[J]. 中国生物医学工程学报(英文版), 2006, 15(3): 134-138 |
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| 作者姓名： | Li Qin-hua Chen Jian-su |
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| 作者单位： | [1]Institute of ltiomedical Engineering, Jinan University, Guangzhou,510632, China [2]Medical College ,Jinan University, Guangzhou,510632, China |
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| 摘 要： | Tissue engineering basically made up growing the relevant cell in vitro and extracellular matrix. A major goal of tissue engineering is to preparate porous three dimension scaffold for cell proliferate, migrate, differention and to form the structure of desirable tissue and organ. In this study, the effects of various content and macromolecular weight of PEG to chitosan were investigated and evaluated. The pore morphology of chitosan was controlled by changing the concentration and macromolecular weight of PEG. Chitosan porous scaffold has interconecting porosity. The pore morphology can be controlled with varying PEG concentration and macromolecular weight. The pore size is between 10～50 urn, the degree of swelling in water is 85.70 % .
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| 关 键 词： | 壳聚糖 形态学 支架 分子学 |
Using PEG as Progen to Preparate Chitosan Scaffold for Tissue Engineering |
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| Li Qin-hua,Chen Jian-su. Using PEG as Progen to Preparate Chitosan Scaffold for Tissue Engineering[J]. Chinese Journal of Biomedical Engineering, 2006, 15(3): 134-138 |
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| Authors: | Li Qin-hua Chen Jian-su |
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| Abstract: | Tissue engineering basically made up growing the relevant cell in vitro and extracellular matrix. A major goal of tissue engineering is to preparate porous three dimension scaffold for cell proliferate, migrate, differention and to form the structure of desirable tissue and organ. In this study, the effects of various content and macromolecular weight of PEG to chitosan were investigated and evaluated. The pore morphology of chitosan was controlled by changing the concentration and macromolecular weight of PEG. Chitosan porous scaffold has interconecting porosity. The pore morphology can be controlled with varying PEG concentration and macromolecular weight. The pore size is between 10~50 um, the degree of swelling in water is 85.70% . |
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| Keywords: | Chitosan scaffolds Porogen Pore morphology |
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