Bulimic Behaviors and Alcohol Use: Shared Genetic Influences |
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Authors: | Jennifer D Slane S Alexandra Burt Kelly L Klump |
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Institution: | (1) Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Office 2433, Ann Arbor, MI 48109-2700, USA;(2) Department of Psychology, Michigan State University, East Lansing, MI, USA |
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Abstract: | Bulimic behaviors are frequently associated with alcohol use disorders. However, extant family and twin study findings have
been inconsistent with regard to whether these behaviors share etiologic influences. A sample of 292 young adult, female twins
was used to examine genetic and environmental factors underlying the association between binge eating and compensatory behaviors
(e.g., vomiting) and alcohol use. Binge eating and compensatory behaviors were assessed using the Minnesota Eating Behavior
Survey. Alcohol use was measured using the Alcohol Use Disorders Identification Test. Univariate models indicated that the
heritability of binge eating, compensatory behaviors, and alcohol use was 41, 28, and 78%, respectively, with the remaining
variance due to nonshared environmental effects. Bivariate models indicated that there was a moderate-to-large degree of overlap
(genetic correlation = 0.31–0.61) in additive genetic factors between alcohol use and binge eating and compensatory behaviors,
and no overlap in environmental effects. Findings suggest that these phenotypes co-aggregate in families and that similar
genes or heritable traits may be contributing to their co-occurrence. |
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Keywords: | |
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