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孕妇弓形虫感染与垂直传播的研究
引用本文:闫旭霞,王新彩,刘润芳,庄建安,李书梅,朱新朋. 孕妇弓形虫感染与垂直传播的研究[J]. 河南医学研究, 2001, 10(2): 162-163
作者姓名:闫旭霞  王新彩  刘润芳  庄建安  李书梅  朱新朋
作者单位:1. 河南省卫生防疫站
2. 洛阳医学高等专科学校
3. 开封市妇产医院
基金项目:洛阳市科委科研基金资助项目
摘    要:目的 :探讨孕妇弓形虫感染对胎儿的影响。方法 :采用酶免三联诊断法对 35 6例母婴配对标本进行血清学检测。结果 :产妇弓形虫感染率平均为 19 1% ,各单项检测分别为循环抗原 (CAg) 15 2 %、IgM2 5 %、IgG3 4% ;新生儿弓形虫感染率平均为 17 7% ,其脐血各单项检测分别为CAg16 9%、IgM0 3%、IgG2 2 %。CAg垂直传播率为 35 2 % ( 19/5 4)。 4例畸胎儿中 1例脐血弓形虫CAg阳性。结论 :孕妇感染弓形虫可通过胎盘垂直感染胎儿 ,应引起围产医务工作者的高度重视 ,加强对弓形虫感染的早期诊断和及时治疗

关 键 词:弓形虫  孕妇  新生儿  循环抗原  垂直传播  畸胎
文章编号:1004-437X(2001)02-0162-02
修稿时间:2001-03-05

Study on toxoplasma infection in pregnant women and its vertical transmission
YAN Xu xia,WANG Xin cai,LIU Run fang,et al. Study on toxoplasma infection in pregnant women and its vertical transmission[J]. Henan Medical Research, 2001, 10(2): 162-163
Authors:YAN Xu xia  WANG Xin cai  LIU Run fang  et al
Abstract:Objective: To observe the influence of Toxoplsma infection from pregnant women to their fet us.Methods:356 cases of mother-baby matched blood samples were taken to detect for the inf ection with Toxoplasma gondii.The Three-Serodiagnosis Regent ELISA were use d to detect circulting antigen(CAg),special antibodies IgM and IgG.Results:The prevelence of Toxoplasma infection in pregnat women is 19.1%,and the three a re CAg 15.2%、IgM 2.5% and IgG 3.4% respectively;that of their new-born babies is 17.7%,and the three are CAg 16.9%、IgM 0.3% adn IgG 2.2% respectively.From th e Matched samples,we know that:the proportion of vertical transmission of CAg is 3562%(19/54).4 babies of congenital malformtion were found.Among the 4,1 sera w as CAg positive.Conclusion:The results we got suggest that about 1/3 fetus will get infection from their mo thers before they give birth.,and the development of fetus can be seriously hurt by toxoplasma gondii infection,which reminds us it is better for woman to t ake examination on toxoplsma before and/or during pregnncy.
Keywords:toxoplasma gondii  pregnant women  new born baby  circulting ntigen  vertical transmission  congenital malformation
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