老年人糖耐量低减者血脂代谢异常的分析

目的探讨老年人糖耐量低减(IGT)患者血脂代谢的改变.方法对39例老年人IGT患者和23例老年人糖耐量正常(NGT)分别检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、载脂蛋白AI(ApoAI)、载脂蛋白B100(ApoB100).结果与NGT组比较,IGT患者TG、IGT患者TG、LDL-C、ApoB100显著升高(P＜0.01),HDL-C明显降低(P＜0.05),且伴总胆固醇有升高趋势及ApoAI有下降的趋势.结论老年人IGT患者存在血脂代谢紊乱以TG、LDL-C、ApoB100升高及HDL-C降低为主,是促使动脉粥样硬化的重要危险因素,应尽早采取降血脂等干预措施予以纠正.

Analysis of lipid metabolism imbalance in aged impaired glucose tolerance

Objective:To study the changes of serum lipid in the aged impaired glucose tolerance.Methods:39 Case impaired glucose tolerance (IGT) of the senile and 23 normal glucose tolerance (NGT) of the senile were examined for total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C);low density lipoprotein-cholesterol (LDL-C), Apolipoprotein AI (ApoAI). and Apolipoprotein B 100 (ApoB 100).Results:In IGT group, the levels of TG, LDL-C, ApoB 100 were significantly higher than those of the NGT group (control group) (P<0.01), and the levels of HDL-C were lower than those in control group (P<0.05). To some extent but not statistically, TC was higher, ApoAI was lower than those of the control group.Conclusions:The main Lipid metabolism imbalance in the IGT are the TG, LDL-C, ApoB 100 increase and the HDL-C decrease,which is the important risk factor of the atheroslerosis (AS). The aged impaired glucose tolerance patients should be intervened of hyperlipidemia as early as possible.