慢性乙型肝炎合并非酒精性脂肪肝患者空腹血糖测定的临床意义

目的 探讨慢性乙型肝炎合并非酒精性脂肪肝患者空腹血糖（GLU）测定的临床意义.方法选择慢性乙型肝炎患者79例,其中单纯慢性乙型肝炎（MCHB）31例,慢性乙型肝炎合并非酒精性脂肪肝（MCHB ＋ NAFLD）48例,正常对照者（N.C）67例,通过四表格χ2检验、方差分析ANOV及两两分析探讨各组与空腹血糖相关性.结果N.C组、MCHB组、MCHB＋NAFLD组,测得各组空腹GLU差异有统计学意义（P〈0.01）,MCHB＋NAFLD患者的空腹血糖升高率明显高于MCHB患者及正常对照组（P〈0.05）.结论慢性乙型肝炎合并非酒精性脂肪肝患者需要密切监测空腹血糖,这是防治脂肪肝的重要措施.

Clinical Significance of the Determination of Fasting Blood Glucose of the Patients with Chronic Hepatitis B Complicated by Nonalcoholic Fatty Liver Disease

Objective To discuss the clinical significance of metLsuring fasting blood glucose（GLU） for patients with both chronic hepatitis B and nonalcoholic fatty liver disease. Methods With the selection of 79 cases of chronic hepatitis B, including 31 cases of chronic hepatitis B（MCHB）, 48 cases of both chronic hepatitis B and nonalcoholic fatty liver disease （MCHB ＋ NAFLD）, 67 cas- es of normal controls （N.C）, examined by four formx2, analysis of variance on ANOV and pairwise comparison, the correlation be- tween each group and fasting blood glucose was discussed. Results There was significant difference in fasting blood glucose be- tween Group N.C, Group MCHB and Group MCHB＋NAFLD （P〈O.O1）. The rising rate of fasting blood glucose in patients with MCHB＋NAFLD was significantly higher than that in patients with MCHB and in normal controls （P〈0.05）. Conclusion Monitoring fasting blood glucose closely is necessary for patients with both chronic hepatitis B and nonalcoholic fatty liver disease, which is an important measure for preventing and treating fatty liver disease.