64例急性有机磷中毒救治过程中继发阿托品中毒的临床分析

目的探讨急性有机磷农药中毒救治过程中继发阿托品中毒的临床分析。方法选择2009年6月～2010年6月期间笔者所在医院收治的急性有机磷农药中毒救治过程中阿托品过量患者157例，并行常规洗胃和应用胆碱脂酶复能剂以及对症支持治疗，并尽早应用阿托品，同时对于继发阿托品中毒患者也应采取相应的救治措施。结果本研究中继发48例（41．40％）不同程度的阿托品中毒，与非阿托品中毒组相比，阿托品中毒组患者的心率和前1h阿托品用量均明显提高，而皮肤干燥的比率则明显降低，差别均具有统计学意义（P〈0．05）。结论对于急性有机磷中毒救助过程中继发阿托品中毒是可以预防和减少的，应积极采取相关措施，明确阿托品反应低下以及阿托品化不明显的原因，力争做到及时发现和对症治疗。

Clinical analysis of treatment of acute organophosphate poisoning atropine poisoning during the secondary in 64 cases

Objective To probe into the clinical analysis of treatment of acute organophosphate poisoning atropine poisoning during the secondary. Methods Selected June 2009 - June 2010 in our hospital during the acute organophosphorus pesticide poisoning treatment of patients over the course of 157 cases of atropine, gastric lavage and application of parallel con- ventional cbolinesterase longer able to support agents and symptomatic treatment, and Early application of atropine, and atro- pine for secondary poisoning patients should take appropriate treatment measures. Results In this study, secondary in 48 pa- tients （41.40%） different levels of atropine poisoning, compared with non - atropine poisoning atropine poisoning, the heart rate and the former group of patients with atropine were significantly increased 1 h, and the skin significantly reduced the rate of drying, there were also significant differences （ P 〈 0. 05 ）. Conclusion For the relief of acute organophosphate poisoning atropine poisoning secondary to the process can be prevented and reduced, should actively take measures, a clear response to the lower atropine and atropine of obvious reasons, strive to ensure timely detection and symptomatic treatment.