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Local Transient Myocardial Liposomal Gene Transfer of Inducible Nitric Oxide Synthase Does Not Aggravate Myocardial Function and Fibrosis and Leads to Moderate Neovascularization in Chronic Myocardial Ischemia in Pigs
Authors:NICO ABEGUNEWARDENE  KAI‐HELGE SCHMIDT  MARKUS VOSSELER  MICHAEL DREHER  TANDIS KELLER  NICO HOFFMANN  KERSTIN VEIT  STEFFEN E. PETERSEN  HANS‐ANTON LEHR  LAURA M. SCHREIBER  TOMMASO GORI  GEORG HORSTICK  THOMAS MÜNZEL
Affiliation:1. 2nd Medical Clinic;2. 1Authors contributed equally to this work and should be considered as joint first and senior authors.;3. Section of Medical Physics, Johannes Gutenberg – University Mainz, Mainz, Germany;4. Sanofi‐Aventis Germany GmbH, TD Cardiovascular Diseases, Frankfurt, Germany;5. University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR), John Radcliffe Hospital, Oxford, UK;6. Centre Hospitalier Universitaire Vaudois, Institut Universitaire de Pathologie, Lausanne, Switzerland
Abstract:
Keywords:inducible nitric oxide synthase  gene therapy  angiogenesis  heart failure
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