Nd:YAG激光刀部分切除兔肝的实验研究

接触式人工蓝宝石Nd:YAG激光刀是在原非接触式Nd:YAG激光刀的基础上发展起来的一种新型手术工具。本研究用动物实验的方法,来比较这两种激光刀的性能。结果表明,新型接触式激光刀在动物肝部分切除上,较非接触式激光刀,切割力强、组织损伤小、操作方便,不易损坏,可投入临床手术中试用。

EXPERIMENTAL STUDY OF PARTIAL HAPATECTOMY WITH CONTACT AND NON-CONTACT ND:YAG LASER IN RABBITS

Hapatectomy was performed in 20 rabbits with a noncontact Nd:YAG laser (group N) and two types of contact Nd:YAG laser(group C-1:type 1,group C-2 and C-3:type 2)which are specially designed artificial sapphire laser scalpels attached to an optic fiber,using different laser parameters,and each group included five animals. Technical aspects and intraoperative and postoperative data were compared.Standardized livercutting times were shorter in all of the contact groups with much lower laser output (C-l:15.osec/cm~2,5w/40w;G-2:47.lsec/cm~2,5w/10w;C-3:16.lsec /cm~2,10w/20w), compared with the non-contact group with high laser power(N:66.5 sec/cm~2,40w).The intraoperative blood losses of all groups were minimal and showed no significant differences among them.Both grossly and histologically,intraoperatively and postoperatively,the contact method caused much less damage to the liver tissue than did the non-contact method.The contact method also resulted in better healing,fibrosis and minimal necrotic material at the cutting place at the 21 postoperative day.There were no deaths or compl(?)cations in the animal groups. Moreover, the contact laser scalpel is easily handled and can resist high temperature and is not easily destroyed, which usually happened to the non-contact laser.