| 大鼠全脑缺血与再灌流后松果腺的形态结构改变 |
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| 引用本文： | 杨亚安,陈尔齐,周先举,王旻晨,刘珺. 大鼠全脑缺血与再灌流后松果腺的形态结构改变[J]. 中国血液流变学杂志, 2001, 11(3): 184-185 |
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| 作者姓名： | 杨亚安 陈尔齐 周先举 王旻晨 刘珺 |
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| 作者单位： | 苏州大学医学院基础医学系解剖学教研室 |
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| 摘 要： | 目的：探讨松果腺在缺血性脑损伤疾病发病机制中的作用。方法：采用阻断大鼠四条动脉的全脑缺血模型,观察缺血30min及再灌流后的不同时间点松果腺形态结构的变化。结果：松果腺细胞出现肿胀、变性和坏死,缺血再灌流后0和12小时,病变以肿胀为主,再灌流24小时后,病变以变性和坏死为主。结论：松果腺分泌褪黑素的能力可能受到影响。
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| 关 键 词： | 脑缺血 再灌流损伤 松果腺 褪黑素 形态结构 大鼠 |
| 文章编号： | 1009-881(2001)03-0184-02 |
| 修稿时间： | 2001-07-10 |
Morphological Changes of Rat Pineal Gland after Whole Cerebral IschemiaReperfusion |
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| YANG Ya an,CHENG Er qi,ZHOU Xian ju,WONG Min chen,Liu Jun.. Morphological Changes of Rat Pineal Gland after Whole Cerebral IschemiaReperfusion[J]. Chinese Journal of Hemorheology, 2001, 11(3): 184-185 |
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| Authors: | YANG Ya an CHENG Er qi ZHOU Xian ju WONG Min chen Liu Jun. |
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| Abstract: | Objective:To study the role of pineal gland in the mechanism of cerebral ischemia disease.Method the whole ischemia model was established by blocking rat four arteries,then morphological changes of pineal gland were observed after 30 minutes ischemia and reperfusion in different time phase.Results pinealocyte were found swelling,degeneration and necrosis.After ischemia reperfusion for 0 and 12 hours,pathological change was mainly found swelling;but for 24 hours,mostly degeneration and necrosis.Conclusion The ability that pineal gland excretes melatonin may be affected. |
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| Keywords: | cerebral ischemia reperfusion pineal gland melatonin |
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