| 高血压病患者粥样硬化性肾动脉狭窄与左心室肥厚的关系 |
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| 引用本文： | 昝朝霞,刘满林,郭永和,成万钧.高血压病患者粥样硬化性肾动脉狭窄与左心室肥厚的关系[J].河北医药,2009,31(14):1707-1709. |
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| 作者姓名： | 昝朝霞 刘满林 郭永和 成万钧 |
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| 作者单位： | 1. 河北省廊坊市第四人民医院,065000
2. 首都医科大学附属北京安贞医院 |
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| 摘 要： | 目的探讨原发性高血压患者粥样硬化性肾动脉狭窄（RAS）与左心室肥厚（LVH）的关系。方法回顾性分析我院因怀疑冠状动脉粥样硬化性心脏病（冠心病）行冠状动脉和肾动脉造影的原发性高血压患者476例，根据肾动脉造影有无RAS将患者分为RAS组和对照组。分别以左心室质量指数（LVMI）标准和左心室壁厚度（IVSd）标准比较2组LVH的发生率，并比较2组LVMI和室间隔厚度（VSd）的差异。结果106例（22．3％）患者存在单侧或双侧RAS。RAS组的LVMI和IVSd均显著高于对照组（P〈0．05），且无论以LVMI还是IVSd作为LVH标准，RAS组LVH发生率均明显高于对照组（P〈0．05）。多因素Logistic回归分析表明，RAS和高血压发病时间（年）、脉压水平以及是否服用血管紧张素转换酶抑制剂（ACEI）或血管紧张素受体拮抗剂（ARB）都是LVH的独立预测因子（P〈0．05）。结论高血压病患者伴发RAS能够进一步促进LVH的发生。
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| 关 键 词： | 高血压 肾动脉狭窄 左心室肥厚 |
The relationship between atherosclerotic renal artery stenosis and left ventricular hypertrophy in patients with primary hypertension |
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| ZAN Zhaoxia,LIU Manlin,GUO Yonghe,et al..The relationship between atherosclerotic renal artery stenosis and left ventricular hypertrophy in patients with primary hypertension[J].Hebei Medical Journal,2009,31(14):1707-1709. |
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| Authors: | ZAN Zhaoxia LIU Manlin GUO Yonghe |
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| Institution: | ZAN Zhaoxia,LIU Manlin,GUO Yonghe,et al.Department of Cardiology,The Fourth People's Hospital of Langfang City,Hebei,Langfang 065000,China |
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| Abstract: | Objective To investigate the relationship between atherosclerotic renal artery stenosis and left ventricular hypertrophy (LVH) in patients with primary hypertension. Methods The data in 476 patients with primary hypertension undergoing coronary and renal angiography were retrospectively analyzed. The patients were divided into two groups according to whether they had atherosclerotic renal artery stenosis (RAS) or not. The incidence of LVH was identified either by left ventricular mass index (LVMI) criteria ... |
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| Keywords: | hypertension renal artery stenosis left ventricular hypertrophy |
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