儿童维生素A缺乏与感染性疾病的关系

[目的]了解儿童血清维生素A缺乏(vitamin A deficiency,VAD)与感染性疾病的关系. [方法]在避光条件下采集儿童指血、分离血清,以严格的质量控制,用微量荧光法检测血清维生素A(vitamin A,VA)浓度. [结果]两周内不同地区儿童发热率、急性呼吸道感染(ARI)、腹泻,发病率随血清VA缺乏率的增加而增加;儿童平均血清VA的含量随发热率、发病率的增加而下降. [结论]我国儿童血清VA含量低、缺乏率高的儿童不论个体或群体都表现为易于发生急性感染疾病,VAD是引起儿童易于发生急性感染性疾病的重要原因之一.

Relationship between vitamin A deficiency and infectious diseases among children

To investigate the relationship between vitamin A deficiency(VAD) and infectious disease. Under the light proof condition, sera vitamin A(VA) concentration was determined by micro fluorescence method from the sera isolated from finger blood under strict quality control. The incidences for fever, acute respiratory tract infection(ARI), diarrhea were positively correlated with the incidence of vitamin A deficiency; the average quantity of vitamin A was negatively correlated with the incidence of fever and other diseases.[Conclusion] In China the individual or group children with low sera vitamin A, high deficiency are more vulnerable to occurrences of infectious disease. This demonstrates that vitamin A deficiency is one of the important factors related to occurrences of acute infectious diseases in children.